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Image: iStock/CR For more information: Maya Brownstein [email protected] ### Harvard T.H

Although ACG normally codes for threonine, in the PRPS1L1 mRNA this alternative start codon directs the initiator methionine for the encoded protein

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All evaluated GLP-1 RAs led to a significant increase in nausea risk, with orforglipron showing the highest risk, followed by exenatide, tirzepatide, semaglutide, and liraglutide

For members with concurrent type 2 diabetes, documentation must show 3 consecutive months of optimal standard of care therapy with all of the following (unless contraindicated or not tolerated): Ozempic or Rybelsus Trulicity Liraglutide (generic Victoza) Mounjaro Documentation of participation in a Health Netapproved weight loss program (e.g., Weight Watchers, Active&Fit) or a prescriber-recommended plan that includes reduced caloric intake, increased physical activity, and lifestyle modification

10.1016/j.medj.2025.100805 Med 30 TangY.WangY.YangG.-Y.ZhangZ.GuoY.ChenT.et al